ProBio Accelerates Development Of COVID-19 Neutralizing Antibodies And Vaccines

COVID-19 emerged as a global threat to human health and many organizations including pharma and biotech are working hard to find the treatments and cure against COVID-19. ProBio has an extensive experience and technical expertise in CDMO space and are trying our best to battle against COVID-19 pandemic.

We can accelerate DNA and RNA vaccine development for drug substance or drug product by providing raw materials or GMP plasmids for vaccine production.

*ProBio made several collaborations with many life sciences groups and pharma companies to develop antibodies against SARS-CoV2 using our Human Antibody Discovery Platforms such as Phage Display, Hybridoma and Single B-Cell Platform.
*To-date, we have screened more than 600 specific RBD (receptor-binding domain) binders and over 100 ACE2 (angiotensin-converting enzyme) blockers.
*We are also offering in vitro pseudovirus neutralization assays for further characterizing the antibodies against SARS-CoV2.
Now, our supply chain is in fully operation at its regular around-the-clock schedule. We have given high priority all the services related to COVID-19.

Related Services

SARS-CoV-2 qRT-PCR Detection Assay

Plasmid manufacturing for vaccines against COVID-19

  • Manufacturing under comprehensive quality assurance process
  • Plasmid manufacturing suitable for pre-clinical to clinical supply
  • Plasmid CMC study for regulatory clearance
Plasmids for SARS-CoV-2 Detection and Research

Pseudovirus Neutralization Assays

The pseudovirus neutralization assay can be used to test the neutralization effect of vaccine or therapeutic lead. We have optimized the pseudovirus designation, packaging, infection and assay workflow by analyzing COVID-19 infection mechanism in our BSL-2 laboratories.

  • Fast delivery: 1-2 weeks to get results
  • High specificity: Ability to specifically screening drugs blocking pseudovirus entry
Peptides, Proteins and Antibodies for COVID-19 Research

ProSpeed Single B-Cell Cloning

  • We can help you to develop fully human therapeutic antibody within 1.5 to 3.5 months!!
  • ProSpeed single B-cell cloning service is very affordable.
  • Therapeutic antibody package including animal immunization.
  • We offer a flexible service that starts from frozen splenocytes/lymphocytes.
Plasmid manufacturing for vaccines against COVID-19

Express IND-Enabling Service

  • Only available for anti-covid-19 antibody project.
  • 5 months to get material for preclinical PK/Tox material, from DNA to GMP batch in 6 months, from DNA to IND filing in 10 months.
SARS-CoV-2 qRT-PCR Detection Assay

In vitro bioassay service for neutralizing antibodies

  • Complete bioassay platform for pre-IND quality research.
  • Ready-to-go assays supporting CMC of neutralizing antibodies.
  • The experimental program, process and report writing are under the strict control of quality management system and GMP-compliant service is also available.
Plasmid manufacturing for vaccines against COVID-19

  • Accelerate COVID19 Antibody Discovery With ProSpeed Single B Cell Technology

    • In this webinar, we introduce single cell technology in immunology and antibody screening, including its emergence, various approaches, benefits, and the current state of its industrial applications. We also introduce background of COVID19, and ProBio ABD platform for COVID19 to accelerate your COVID19 antibody discovery.

  • Robust Stable Cell Line Platform for Biologics Developme

    • A cell line platform can provide the best solution for the biopharmaceutical target. ProBio’s biologics platform can provide one-stop service of CMC for the biopharmaceutical target. In this webinar we introduce key technologies in cell line development and discuss how to achieve desired cell lines. We also share several cell line development case studies from ProBio.