By Jul 2022

  • 1   Growth inhibition assay;
  • 2   GPCR-targeted agonist/antagonist assay;
  • 3   Neutralization assay;
  • 4   Immune checkpoint-targeted reporter gene assay;
  • 5   Customized functional assay cell line construction;
  • 6   Immune cell stimulation and multiplex cytokine release assay;
  • 7   Mixed lymphocyte reaction;
  • 8   Complement-dependent cytotoxicity assay;
  • 9   Antibody-dependent cell cytotoxicity assay;
  • 10   Antibody-dependent cellular phagocytosis assay;
  • 11   Cellular characterization assay by flow cytometry;
  • 12   Pseudovirus neutralization assay;
  • 13   Internalization assay;
  • 14   Bispecific antibody assay;

Target Based Bioassay Summary List from ProBio

Based on our 14 years of experience in bioassay services, ProBio has compiled a cell-based bioassay list for different targets, please click to download!

Target FACS binding assay Reporter gene assay Primary immune cell assay Fc function Antibody internaliztion Enzyme activity assay Cell proliferation / apoptosis
Human Other species Cytotoxicity Assay Cytokines release Cell proliferation MLR assay FACS(CD25,CD69, ect.) ADCC CDC ADCP
Claudin 18.2 Y Y Y Y Y Y
PD-1 Y Y Y Y
PD-L1 Y Y Y Y Y
PD-L2 Y Y
Her-2 Y Y Y Y
CD19 Y
CD20 Y Y Y Y Y
B7-H3 Y Y Y Y Y
BCMA Y Y Y Y
CCR8 Click here for a complete list of in vitro bioassays based on 70+ targets
CD112
CD112R
CD155
CD16
Claudin 6
CTLA4
EGFR
FcRn
ROR1