GMP LVV Manufacturing Service
With the rapid development, more and more programs that using lentiviral vectors (LVV) have finished clinical trials, and been ready for commercialization. ProBio has worked with global customers and is able to provide GMP LVV from clinical phases to commercialization in both adherent and suspension cultures, starting from either cell bank or plasmid manufacturing plasmid manufacturing.
ProBio LVV Manufacturing
ProBio is experienced in manufacturing lentiviral vectors adopting both adherent system and suspension system. We use licensed PowerATM-293T cell lines, and developed our proprietary suspension cell line PowerSTM-293T, with the production capacity from 2L to 200L.
Our experts will discuss your project with you in detail and propose a best solution to accelerate your project.
Suspension Culture System
- Proprietary cell line PowerSTM-293T
- Stable and scalable suspension manufacturing process
- up to 200L manufacturing scale
- 4~5 times final yield improvement comparing with adherent culture system
- ~50% cost reduction
- High T cell transduction efficiency
PowerSTM-293T
- Proprietary Suspension cell line
- License for IND, clinical and commercial
- Royalty free, maintenance free
- Excellent performance in producing lentiviral vector
LVV Production: PowerSTM-293T with Different GOI
Crude titer up to 108 TU/ml
Adherent Culture System
- The largest manufacturing scales is Up to 96L
- Closed culture system reduces contamination and improves stability
- Full-automatic operation improves reproducibility and stability
Accumulated Experience
ProBio has accumulated rich experience in manufacturing lentiviral vector, which guaranteed a dedicated and professional service for customers.
- Worked with global clients for their LVV projects
- Provided GMP lentiviral vector for CAR-T, TCR-T projects
- Over 100 GMP manufacturing batches experience
