AAV Manufacturing

Pro AAV Manufacturing

Clinical GMP AAV Manufacturing

Adeno-associated virus (AAV) was first found in 1965 in the lab. Recent years, with the development of the technology and research, AAV vector becomes the popular delivery platform. ProBio, using its proprietary suspension cell line PowerS™-293, with triple transient transfection system, provides a robust and high-quality AAV vector manufacturing platform. The platform is suitable for serotypes including AAV2/5/8/9 and other engineering AAV. Though the high-standard quality control, ProBio is able to serve customers in different development stages including preclinical, clinical and IND filing, etc.

Triple Transient Transfection System Process

• 1 helper plasmid + 1 Rep/Cap plasmid + 1 transfer plasmid
• Co-transfection of 3 plasmids in HEK293 cells
• Proprietary suspension cell line PowerS™-293